Nano- / Micro-emulsions
Colloidal Drug/Gene Delivery Systems: Polymeric Micelles, Vesicles, Physical Gels
Enantiomeric Separations by Capillary Electrophoresis
A major area of our research is concerned with the self-assemblies (such as micelles, vesicles, physical gels etc.) of synthetic biocompatible surfactants and polymers in both aqueous and non-aqueous media. With a wide range of techniques (fluorescence, UV-visible spectroscopy, rheology, static and dynamic light scattering, light and electron microscopy, etc.), our group is interested in how these self-assembled micro/nano-structures could be used as stimuli-responsive drug/gene delivery system. Furthermore, the group is also interested in unraveling the interactions of these self-assemblies with macromolecules, in particular with transport proteins.
We have a program of research aimed at enantioseparations of drugs, pesticides, and small organic racemates by electrokinetic capillary chromatography (EKC). This technique uses self-assemblies of optically pure surfactant monomers as well as polymers as pseudo-stationary phases. Our group has been able to demonstrate improved selectivity and optical resolution of enantiomers by use of vesicles.
- DLS: Spectro SizeTM 300 Nano Biochem Technology
- Spectrofluorimeter: PerkinElmer LS55 Luminescence Spetrometer
- Surface Tensiometer: 3S GBX, France
- Lyophilizer: VaCO 2 Zirbus Technology
- Weighing Balance: Model CP 225D, Satorious
- Refractometer: RI-1-4 refractometer, Shodex
- Rotational Rheometer: Rheolab QC, Anton Paar
- Rotary Evaporator: Heidolph