Extensive experience in linear spectroscopy
Nonlinear laser spectroscopy
Time resolved studies in photochemistry
Femtosecond fluorescence up-conversion technique
Fluorescence spectroscopy in organized assemblies, surface second harmonic generation (SSHG) and magnetic field effect in small molecules in the gas phase
Spectroscopy in Room temperature ionic liquids (RTILs)
Characterization of Micelles, Reverse Micelles, Microemulsions in Room temperature ionic liquids (RTILs).
Synthesis and optical properties of metal nanoparticles in aqueous and non-aqueous reverse micelles and investigation of solvent relaxation in reverse micelle.
Fluorescence Correlation Spectroscopy and fluorescence life time imaging
The self assembly behaviour of 5-fluorouracil and N,N-dimethyl derivative, 5-fluoro-1,3-dimethyluracil under physiological conditions was explored. This self-assembly of 5-FU compared with its N,N-dimethyl derivative also showed lower cytotoxicity to K562 cells.
An anionic lipophilic dye, MC540 and cationic SAIL, C8mimCl employed to construct highly ordered fibrillar and vesicular aggregates. The synergistic interplay of electrostatic, hydrophobic, and pi-pi stacking interactions to construct the self-assembly and their concentration-dependent morphological transition was also explored.
The synthesis of BSA and HSA fibrils and the effect of three amphiphilic SAILs- C8mimCl, C12mimCl and C16mimCl was explored which showed that all these three SAILs have different extent of fibril inhibition effect.
A novel L-glycine amino acid derived cholesterol based SAIL has been explored for the preparation of IL-in-oil microemulsions and vesicles. These aggregates may potentially serve as good biomimicking models and possible drug carriers.
The location as well as the photo physical behaviours of hydrophobic C153 and hydrophilic R6G during micelle-vesicle-micelle transition of aqueous anionic surfactant, SDBS and imidazolium containing cationic surfactants was investigated.
Protein-capped silver NCs impregnated onto graphene oxide (GO) sheets was internalized into the K562 cell and the Ag NCs/GO assembly can act as a synergistic drug carrier for Imatinib along with this Ag NCs adsorbed on GO have a great potential to be used as X-ray computer tomography (CT) imaging contrasting agents.
The interaction of L-phenylalanine fibrils with two crown ethers- 15C5 and 18C6 was explored. Although, both the crown ethers have the ability to arrest fibril formation, but 18C6 was found to be a better candidate compared to 15C5.
The interaction between different sugars (sucrose, trehalose, and maltose) and phospholipid membrane of 1,2- dimyristoyl-sn-glycero-3-phoshpocholine (DMPC) was investigated. The effects of different sugars on the rotational relaxation and solvation times of C480 and C153 surrounding DMPC membrane were also explored.
The formation of vesicles in aqueous solution of oleate ethyl amine and further the effect of NaCl was unveiled. The rich dynamic properties of this vesicular assembly and the vesicle fusion will further provide better insight into the growth of a protocell membrane.
Protein Dynamics in Graphene Oxide Sheets through FLIM and FCS
Fluorescence Lifetime Imaging Microscopy of Hela Cell
CT-DNA and Berberine Cation in Confined Environment of Reverse Micelles
Intramolecular Proton Transfer of 1’-Hydroxy-2’-acetonaphthone (HAN) in cucurbit 7 uril
Excited State Intermolecular Proton Transfer of D-Luciferin in AOT Reverse Micelle
Micelle to Vesicle Transition from Triblock Copolymers
Curcumin in Polymeric Nanoparticles
A New Strategy for the Formation of IL-in-Oil Microemulsions and Spontaneous Vesicles
Facile Methods to Tune Structural Properties of Ionic liquid-in-Oil Microemulsions
Synthesis of Nano Particles in Micelles: A Study of Controlled Nanometal Surface Energy Transfer (NSET)
Modulation of the Photophysical Properties of Proton Transfer Chromophores inside Nanocavities
Project Title : Synthesis, Characterization and Applications of Surface Active Ionic Liquids (SAILs) forming Self-assemblies and Investigation of Dynamical Process .
Funding agency: CSIR, Period: 01-10-2014 to 30-09-2017
Project Title : Femtosecond Laser Facility to Investigate Confined Media, Biological Assemblies. Room Temperature Ionic Liquids and Nano-Materials.
Funding agency: SERB (DST) 27-03-2015 to 26-03-2020
Project title: ‘Characterization of Ionic Liquid containing microheterogeneous media and Investigation of Ultrafast Processes in these confined media’.
Funding agency: CSIR, Period: 01-02-2011 to 31-01-2014
Project title: ‘Synthesis and optical properties of metal nanoparticles in aqueous and non-aqueous reverse micelles and investigation of solvent relaxation in reverse micelles in presence of metal nanoparticles’.
Funding Agency: BRNS, Period: 16-02-2009 to 15-02-2012.
Project title: ‘Study of ultrafast processes in ionic liquid containing micro heterogeneous media’.
Funding agency: CSIR, Period: 12-05-2006 to 11-05-2009
Project title: ‘Characterization of Micelles, Reverse Micelles in Room temperature ionic liquids (RTILs) using Dynamic Light Scattering, Fluorescence Spectroscopy and use of these novel systems for photophysical, dynamical studies and nanoparticle synthesis’.
Funding agency: DST, Period: 01/10/2007 to 30/09/2010
Project Title: ‘Spectroscopic Study of Photochemical reactions and solvation dynamics in solution and organized assemblies’.
Funding Agency: CSIR, Period: July, 2000 to June, 2003.
Project Title: ‘Photoinduced electron and energy transfer of some organic molecules in biologically relevant organized media’.
Funding Agency: DST, Period: November, 2001 to October, 2004.
Project Title: ‘Ultrafast Spectroscopic Study of Solvation and Photochemical reactions in solution and organized assemblies’.
Funding Agency: ISIRD, IIT-Kharagpur, Period: August, 1998 to July 2000.
- No. of Publications: 188
- No of Ph. D. Students supervised & being supervised: 23
- No of M. Sc. Students supervised & being supervised: 22
- No of Sponsored Research Projects completed: 07