Profile

tpathak@chem.iitkgp.ac.in

Research Statement

Publications

Journal Publications

Mandal, M. Ghosh, B. Anura, A. Mitra, P. Pathak, T. Chatterjee, J. , "Modeling continuum of epithelial mesenchymal transition plasticity " Integrative Biology, 8, 167-176 (2016), 2016
Kayet, A. Ganguly, A. Pathak, T. , "Vinyl sulfone modified-azidofuranoside buildin gblocks: 1,4-/1,5-disubstituted-1,2,3-triazole linked trisaccharides via an aqueous/ionic-liquid route and “Click” chemistry " RSC Advances, 6, 7977-7981 (2016), 2016
Bhaumik, A. Pal, T. K. Pathak, T. , "1,1-Dioxothiomorpholines with Asymmetric Environments: Protecting Group Directed Diastereoselectivity of Glyco Divinyl Sulfone Cyclization. " RSC Adv, 5, 27706 - 27710 (2015), 2015
Bhaumik, A. Pal, T. K. Pathak, T. , "Methyl-alpha-D-2-selenonyl pent-2-enofuranoside: A Unique Selenosugar for the Diversity Oriented Synthesis of Enantiomerically Pure Heterocycles, Carbocycles and Isonucleosides. " J. Org. Chem., 80, 11057–11064 (2015), 2015
Dey, T. Kundu, B. Dey, D. Pathak, T. Kundu. S. C. , "Cytotoxicity and Sustained Release of Modified Divinylsulfone from Silk based 3D Construct. " J Mater Sci: Mater Med, 26, 263-270 (2015), 2015
Kayet, A. Dey, S. Pathak, T. , "A Metal Free Aqueous Route to 1,5-Disubstituted 1,2,3-Triazolylated Monofuranosides and Difuranosides." Tetrahedron Lett., 56, 5521-5524 (2015), 2015
Datta, D. Bera, R. K. Jana, S. Manna, B. Roy, D. Anoop, A. Raj, C. R. Pathak, T., "A Rationally Designed Thymidine-based Self-assembled Monolayer on Gold Electrode for Electroanalytical Applications." Chem. Asian J., 10, 1554-1560 (2015), 2015
Chakraborty, K. Swagata Dasgupta, S. Pathak, T. , "Carboxylated Acyclonucleosides: Synthesis and RNase A Inhibition. " Molecules, 20, 5924-5941 (2015), 2015
Debnath J. Dasgupta S. Pathak T. , "Amino and carboxy functionalized modified nucleosides: A potential class of inhibitors for angiogenin. " Bioorg. Chem., 52, 56-61 (2014), 2014
Datta, D. Samanta, A. Dasgupta, S. Pathak, T , "Synthesis of 5’-carboxymethylsulfonyl-5’-deoxy-ribonucleosides under mild hydrolytic conditions: a new class of acidic nucleosides as inhibitors of ribonuclease A. " RSC Advances, 4, 2214-2218 (2014), 2014
Dey, S. Pathak, T. , "A general route to 1,5-disubstituted 1,2,3-triazoles with alkyl/alkyl, alkyl/aryl, aryl/aryl combinations: a metal-free, regioselective, one-pot three component approach. " RSC Adv, 4, 9275–9278 (2014), 2014
Datta, D. Dasgupta, S. Pathak, T. , "Ribonuclease A Inhibition by Carboxymethylsulfonyl-Modified Xylo- and Arabinopyrimidines. " ChemMedChem, 9, 2138-2149 (2014), 2014
Bhaumik, A. Samanta, S. Pathak, T. , "Enantiopure 1,4,5-Trisubstituted 1,2,3-Triazoles from Carbohydrates: Applications of Organoselenium Chemistry. " J. Org. Chem., 79, 6895-6904 (2014), 2014
Sahu,D. Dey,S. Pathak, T. , "Probing the reactivity of vinyl sulfone based 1,3-dipolar cycloaddition reactions with sugar azides in metal free condition: computational and experimental study. " Org. Lett., 16, 2100-2103 (2014), 2014
Kayet, A. Datta, D. Kumar, G. Ghosh, A. S. Pathak, T. , "Templating effect of 1,5-disubstituted 1,2,3-triazole-linked disaccharides on size, shape and antibacterial activity of silver nanoparticles. " RSC Adv, 4, 63036-63039 (2014), 2014
Dey, S., Datta, D. Chakraborty, K. Nandi, S. Anoop, A. Pathak, T. , "A coordination-assisted general approach to nickel-based nano metallogels. " RSC Adv., 3, 9163-9166. (2013), 2013
Manna, C. Samanta, S. K. Ghosh, S. K. Pathak, T. , "Synthesis of 1,8-dioxooctahydroxanthene C-nucleosides. " Tetrahedron Lett., 54, 3971-3973. (2013), 2013
Datta, D. Samanta, A. Dasgupta, S. Pathak, T. , "3`-Oxo-, amino-, thio- and sulfone-acetic acid modified thymidines: effect of increased acidity on ribonuclease A inhibition " Bioorg. Med. Chem., 21, 4634-4645 (2013), 2013
Dey, D. Bhaumik, A. Pathak, T. , "Vinyl sulfone- and vinyl sulfoxide-modified tetrahydrofurans: a preliminary account of the enantiomeric synthesis of and diastereoselectivity of addition to new classes of michael acceptors. " Tetrahedron, 69, 8705-8712 (2013), 2013
Manna, C. Pathak, T. , "Reactions of beta-dicarbonyls with a vinyl sulfone-modified polyol: from D-xylose to densely functionalized carbocycles (A special issue in memory of Prof. D. Loganathan) " Trend. Carbohydr. Res., 5, 53-58 (2013), 2013
Manna, C. Pathak, T. , "Diversity oriented synthesis of enantiopure furofurans from carbohydrates: an expedient approach with built-in michael acceptor, masked aldehyde and leaving group in a single sugar derivative. " Eur. J. Org. Chem., 27, 6084-6097 (2013), 2013
Kayet, A. Pathak, T. , "1, 5-Disubstituted 1,2,3-triazolylation at C1, C2, C3, C4 and C6 of pyranosides: A metal-free route to triazolylated monosaccharides and triazole-linked disaccharides " J. Org. Chem., 78, 9865-9875 (2013), 2013
Bhattacharya, R. Pathak, T. , "Influence of steric bulk around the vinyl sulfone bond on the reaction patterns of vinyl sulfone-modified carbohydrates (A special issue in honor of Prof. S. K. Talapatra) " J. Ind. Chem. Soc., 90, 1-8 (2013), 2013
Manna, C. Sahu, D. Ganguly, B. Pathak, T. , "Furo[2,3-c]pyrans from a Vinyl Sulfone Modified Methyl 2,6-O-Anhydro-alpha-D-hexopyranoside: An Experimental and Theoretical Investigation " Eur. J. Org. Chem., 8197-8207 (2013), 2013

Projects

Molecular analysis of efflux pump mediated antibiotic resistance in Gram negative bacilli (MGB)
Client: DBT
PI: Anindya Sundar Ghosh (BT)  |  Co-Consultant(s): T. Pathak
New Polymers and Polymer Composites: Design, Symthesis and Advanced Applications
Client: D. Dhara and others
PI: T. Pathak  |  Co-Consultant(s): SGDRI
A Journey to the Centre of Ribonucleases: Designing of Nucleoside-based Inhibitors
Client: DBT
PI: T. Pathak  |  Co-Consultant(s): Swagata Dasgupta
A Metal-Free, General Synthetic Strategy for 1,5-Disubstituted-1,2,3- triazoles: New Chemical Entities for Biological- and Material- Sciences
Client: DST
PI: T. Pathak  |  Co-Consultant(s):

Awards and Recognition

No awards on record.

Courses Taught

No courses listed.

Patents

No patents on record.

Research Group

Current Members

AMITABHA BOSE
AMITABHA BOSE
Synthesis of heterocycles as new chemical entities
amitabha92bose@iitkgp.ac.in
ASHRUKANA DAS
ASHRUKANA DAS
Inhibition of ribonucleases with synthetic carbohydrates
ashrukanachem@iitkgp.ac.in
KUMARES SARKAR
KUMARES SARKAR
Synthesis and properties of functionalized triazoles
sarkarkumares11@gmail.com
PAMPA MONDAL
PAMPA MONDAL
Inhibition of ribonucleases with synthetic nucleosides
m.pampacu@gmail.com
RAJESH MAITI
RAJESH MAITI
Vinyl nitro-modified carbohydrates
rmaiti15292@gmail.coM
RASHMITA PAN
RASHMITA PAN
biologically relevant triazoles
rpan0007@gmail.com
SUBHANKAR SANTRA
SUBHANKAR SANTRA
Heterocyclic chemistry
subha95santra@gmail.com